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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MATK All Species: 6.06
Human Site: S499 Identified Species: 12.12
UniProt: P42679 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42679 NP_002369.2 507 56469 S499 S G Q D A D G S T S P R S Q E
Chimpanzee Pan troglodytes XP_512276 328 36052 T321 G Q D A D G S T S P R S Q E P
Rhesus Macaque Macaca mulatta XP_001101430 450 50702 I443 L R E Q L E H I K T H E L H L
Dog Lupus familis XP_854815 843 91685 T808 S S G H S P S T P C T Q S R R
Cat Felis silvestris
Mouse Mus musculus P41242 505 56038 S497 G G Q E A E G S A P T R S Q D
Rat Rattus norvegicus P41243 467 51878 A460 G Q E A E G S A P T R S Q D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P41239 450 50733 I443 L R E Q L V H I K E K E L Y L
Frog Xenopus laevis P13116 532 59718 Q525 Y F T A T E P Q Y Q P G D N L
Zebra Danio Brachydanio rerio XP_695792 445 50295 E438 H K L R E R L E K E L K L H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731611 1052 113728 K1043 T F A E L K V K L Q L L N N A
Honey Bee Apis mellifera XP_393399 493 55500 A486 L V L G Q L K A E Y T K G V N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795344 763 85563 Q756 T F K H V R S Q L N L F M S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.6 47.1 56.8 N.A. 87.1 82.2 N.A. N.A. 46.9 34 56 N.A. 24.8 40 N.A. 32.2
Protein Similarity: 100 64.6 64.6 58.8 N.A. 92.3 87.5 N.A. N.A. 65.6 49.2 71.4 N.A. 33.1 57.5 N.A. 42.9
P-Site Identity: 100 0 0 13.3 N.A. 53.3 0 N.A. N.A. 0 6.6 0 N.A. 0 0 N.A. 0
P-Site Similarity: 100 20 20 40 N.A. 73.3 20 N.A. N.A. 6.6 13.3 6.6 N.A. 20 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 25 17 0 0 17 9 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 9 9 9 9 0 0 0 0 0 0 9 9 9 % D
% Glu: 0 0 25 17 17 25 0 9 9 17 0 17 0 9 9 % E
% Phe: 0 25 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 25 17 9 9 0 17 17 0 0 0 0 9 9 0 0 % G
% His: 9 0 0 17 0 0 17 0 0 0 9 0 0 17 0 % H
% Ile: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % I
% Lys: 0 9 9 0 0 9 9 9 25 0 9 17 0 0 0 % K
% Leu: 25 0 17 0 25 9 9 0 17 0 25 9 25 0 25 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 0 9 17 9 % N
% Pro: 0 0 0 0 0 9 9 0 17 17 17 0 0 0 17 % P
% Gln: 0 17 17 17 9 0 0 17 0 17 0 9 17 17 0 % Q
% Arg: 0 17 0 9 0 17 0 0 0 0 17 17 0 9 17 % R
% Ser: 17 9 0 0 9 0 34 17 9 9 0 17 25 9 0 % S
% Thr: 17 0 9 0 9 0 0 17 9 17 25 0 0 0 9 % T
% Val: 0 9 0 0 9 9 9 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 9 9 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _